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1

Platelet biology and functions: new concepts and clinical perspectives

van der Meijden, Paola E. J., Heemskerk, Johan W. M.

Journal:

Nature Reviews Cardiology (formerly Nature Clinical Practice Cardiovascular Medicine)

Year:

2018

Language:

english

File:

PDF, 2.42 MB

english, 2018

2

Separation of chloroplast polar lipids and measurement of galactolipid metabolism by high-performance liquid chromatography

Johan W.M. Heemskerk, Gerard Bögemann, Martin A.M. Scheijen, J.F.G.M. Wintermans

Journal:

Analytical Biochemistry

Year:

1986

Language:

english

File:

PDF, 514 KB

english, 1986

3

Performance of an easy-to-use prediction model for renal patient survival: an external validation study using data from the ERA-EDTA Registry

Hemke, Aline C, Heemskerk, Martin B A, van Diepen, Merel, Kramer, Anneke, de Meester, Johan, Heaf, James G, Abad Diez, José Maria, Torres Guinea, Marta, Finne, Patrik, Brunet, Philippe, Vikse, Bjørn E

Journal:

Nephrology Dialysis Transplantation

Year:

2018

Language:

english

File:

PDF, 270 KB

english, 2018

4

Whole Blood Based Multiparameter Assessment of Thrombus Formation in Standard Microfluidic Devices to Proxy In Vivo Haemostasis and Thrombosis

Provenzale, Isabella, Brouns, Sanne L. N., van der Meijden, Paola E. J., Swieringa, Frauke, Heemskerk, Johan W. M.

Journal:

Year:

2019

Language:

english

File:

PDF, 1.31 MB

english, 2019

5

Metapsychology of the creative process

Heemskerk, Johan

Journal:

Philosophical Psychology

Year:

2020

Language:

english

File:

PDF, 518 KB

english, 2020

6

Spinal Growth in Patients With Juvenile Idiopathic Scoliosis Treated With Boston Brace

Heemskerk, Johan L., Wijdicks, Sebastiaan P.J., Altena, Mark C., Castelein, RenÃ© M., Kruyt, Moyo C., Kempen, Diederik H.R.

Journal:

Year:

2020

File:

PDF, 787 KB

2020

7

Inter-individual variability in Ca2+ signalling in platelets from healthy volunteers: effects of aspirin and relationship with expression of endomembrane Ca2+-ATPases

Marion A. H. Feijge, Elisabeth C. M. Van Pampus, Christine Lacabaratz-Porret, Karly HamulyÀk, Sylviane Lévy-Toledano, Jocelyne Enouf, Johan W. M. Heemskerk

Journal:

British Journal of Haematology

Year:

1998

Language:

english

File:

PDF, 846 KB

english, 1998

8

Irregular spiking in free calcium concentration in single, human platelets : Regulation by modulation of the inositol trisphosphate receptors

Roosje M. A. van Gorp, Marion A. H. Feijge, Wim M. J. Vuist, Martin B. Rook, Johan W. M. Heemskerk

Journal:

Year:

2002

Language:

english

File:

PDF, 534 KB

english, 2002

9

[(3-13C)-3-Aminopropyl]triethoxysilane; synthesis and spectral characterization of 13C-substituted compounds

Leonardus W. Jenneskens, Ellen M. M. van den Berg, Bram Heemskerk, Johan Lugtenburg

Journal:

Recueil des Travaux Chimiques des Pays-Bas

Year:

1988

Language:

english

File:

PDF, 438 KB

english, 1988

10

Synthesis of indoles and L-tryptophans specifically 2H- or 13C-labelled in the six-membered ring

Ellen M. M. van den Berg, Willem B. S. van Liemt, Bram Heemskerk, Johan Lugtenburg

Journal:

Recueil des Travaux Chimiques des Pays-Bas

Year:

1989

Language:

english

File:

PDF, 1.27 MB

english, 1989

11

Decreased responsiveness and development of activation markers of PLTs stored in plasma

Joyce Curvers, Elisabeth C.M. Van Pampus, Marion A.H. Feijge, Eva Rombout-Sestrienkova, Peter L.A. Giesen, Johan W.M. Heemskerk

Journal:

Transfusion (Wiley)

Year:

2004

Language:

english

File:

PDF, 198 KB

english, 2004

12

Novel methodology for assessment of prophylactic platelet transfusion therapy by measuring increased thrombus formation and thrombin generation

Sandra Cauwenberghs, Marion A. H. Feijge, Evi Theunissen, Johan W. M. Heemskerk, Elisabeth C. M. Van Pampus, Joyce Curvers

Journal:

British Journal of Haematology

Year:

2007

Language:

english

File:

PDF, 762 KB

english, 2007

13

Role of the chloroplast in the leaf acyl-lipid synthesis

Johan W. M. Heemskerk, Jef F. G. M. Wintermans

Journal:

Physiologia Plantarum

Year:

1987

Language:

english

File:

PDF, 10.27 MB

english, 1987

14

Ragged spiking of free calcium in ADP-stimulated human platelets: regulation of puff-like calcium signals in vitro and ex vivo

Johan W. M. Heemskerk, , Martin B. Rook, Stewart O. Sage

Journal:

The Journal of Physiology

Year:

2001

Language:

english

File:

PDF, 529 KB

english, 2001

15

Platelet ADP response deteriorates in synthetic storage media

Jeffrey F.W. Keuren, Sandra Cauwenberghs, Judith Heeremans, Wim De Kort, Johan W.M. Heemskerk, Joyce Curvers

Journal:

Transfusion (Wiley)

Year:

2006

Language:

english

File:

PDF, 212 KB

english, 2006

16

Plasma ectonucleotidases prevent desensitization of purinergic receptors in stored platelets: importance for platelet activity during thrombus formation

Sandra Cauwenberghs, Marion A.H. Feijge, Geja Hageman, Marc Hoylaerts, Jan-Willem N. Akkerman, Joyce Curvers, Johan W.M. Heemskerk

Journal:

Transfusion (Wiley)

Year:

2006

Language:

english

File:

PDF, 354 KB

english, 2006

17

Effects of plasma dilution on tissue factor–induced thrombin generation and thromboelastography: partly compensating role of platelets

Saskia E.M. Schols, Marion A.H. Feijge, Marcus D. Lancé, Karly Hamulyák, Hugo Ten Cate, Johan W. M. Heemskerk, Elisabeth C.M. Van Pampus

Journal:

Transfusion (Wiley)

Year:

2008

Language:

english

File:

PDF, 377 KB

english, 2008

18

Dual P2Y12 receptor signaling in thrombin-stimulated platelets – involvement of phosphoinositide 3-kinase β but not γ isoform in Ca2+ mobilization and procoagulant activity

Paola E. J. van der Meijden, Simone M. Schoenwaelder, Marion A. H. Feijge, Judith M. E. M. Cosemans, Imke C. A. Munnix, Reinhard Wetzker, Regine Heller, Shaun P. Jackson, Johan W. M. Heemskerk

Journal:

Year:

2008

Language:

english

File:

PDF, 1.29 MB

english, 2008

19

Accurate quantification of dystrophin mRNA and exon skipping levels in Duchenne Muscular Dystrophy

Spitali, Pietro, Heemskerk, Hans, Vossen, Rolf HAM, Ferlini, Alessandra, den Dunnen, Johan T, 't Hoen, Peter AC, Aartsma-Rus, Annemieke

Journal:

Laboratory Investigation

Year:

2010

Language:

english

File:

PDF, 292 KB

english, 2010

20

Facilitating roles of murine platelet glycoprotein Ib and αIIbβ3 in phosphatidylserine exposure during vWF–collagen-induced thrombus formation

Marijke J. E. Kuijpers, Valerie Schulte, Cécile Oury, Theo Lindhout, Jos Broers, Marc F. Hoylaerts, Bernhard Nieswandt, Johan W. M. Heemskerk

Journal:

The Journal of Physiology

Year:

2004

Language:

english

File:

PDF, 291 KB

english, 2004

21

Regulation of Microvascular Thromboembolism In Vivo

MIRJAM G. A. OUDE EGBRINK PhD, MIRIAM A. VAN GESTEL PhD, MARTIJN A. W. BROEDERS MD, PhD, GEERT JAN TANGELDER MD, PhD, JOHAN M. W. HEEMSKERK PhD, ROBERT S. RENEMAN MD, PhD, DICK W. SLAAF PhD

Journal:

Microcirculation

Year:

2005

Language:

english

File:

PDF, 1.88 MB

english, 2005

22

Both ADP and Thrombin Regulate Arteriolar Thrombus Stabilization and Embolization, but Are Not Involved in Initial Hemostasis as Induced by Micropuncture

Miriam A. Van Gestel, Sietze Reitsma, Dick W. Slaaf, Viviane V. Th. Heijnen, Marion A. H. Feijge, Theo Lindhout, Marc A. M. J. Van Zandvoort, Margareta Elg, Robert S. Reneman, Johan W. M. Heemskerk, M

Journal:

Microcirculation

Year:

2007

Language:

english

File:

PDF, 2.38 MB

english, 2007

23

Key Role of Platelet Procoagulant Activity in Tissue Factor-and Collagen-Dependent Thrombus Formation in Arterioles and Venules In Vivo Differential Sensitivity to Thrombin Inhibition

Marijke J.E. Kuijpers, Imke C.A. Munnix, Judith M.E.M. Cosemans, Bart J. Van Vlijmen, Chris P.M. Reutelingsperger, Mirjam G.A. Oude Egbrink, Johan W.M. Heemskerk

Journal:

Microcirculation

Year:

2008

Language:

english

File:

PDF, 4.74 MB

english, 2008

24

Polyphosphates: a link between platelet activation, intrinsic coagulation and inflammation?

van der Meijden, Paola EJ, Heemskerk, Johan WM

Journal:

Expert Review of Hematology

Year:

2010

Language:

english

File:

PDF, 215 KB

english, 2010

25

Phage display screening without repetitious selection rounds

Peter A.C. ’t Hoen, Silvana M.G. Jirka, Bradley R. ten Broeke, Erik A. Schultes, Begoña Aguilera, Kar Him Pang, Hans Heemskerk, Annemieke Aartsma-Rus, Gertjan J. van Ommen, Johan T. den Dunnen

Journal:

Analytical Biochemistry

Year:

2012

Language:

english

File:

PDF, 1009 KB

english, 2012

26

Cell-to-cell variability in the differentiation program of human megakaryocytes

Els den Dekker, Monique van Abel, Hans van der Vuurst, Guillaume J.J.M. van Eys, Jan-Willem N. Akkerman, Johan W.M. Heemskerk

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

2003

Language:

english

File:

PDF, 360 KB

english, 2003

27

Factor Xa and thrombin evoke additive calcium and proinflammatory responses in endothelial cells subjected to coagulation

Valéry Daubie, Sandra Cauwenberghs, Nicole H.M. Senden, Roland Pochet, Theo Lindhout, Wim A. Buurman, Johan W.M. Heemskerk

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

2006

Language:

english

File:

PDF, 628 KB

english, 2006

28

Control of platelet activation by cyclic AMP turnover and cyclic nucleotide phosphodiesterase type-3

Marion A.H Feijge, Karin Ansink, Kristof Vanschoonbeek, Johan W.M Heemskerk

Journal:

Biochemical Pharmacology

Year:

2004

Language:

english

File:

PDF, 252 KB

english, 2004

29

Unravelling the different functions of protein kinase C isoforms in platelets

Johan W.M. Heemskerk, Matthew T. Harper, Judith M.E.M. Cosemans, Alastair W. Poole

Journal:

Year:

2011

Language:

english

File:

PDF, 418 KB

english, 2011

30

The quercetin paradox

Agnes W. Boots, Hui Li, Roel P.F. Schins, Rodger Duffin, Johan W.M. Heemskerk, Aalt Bast, Guido R.M.M. Haenen

Journal:

Toxicology and Applied Pharmacology

Year:

2007

Language:

english

File:

PDF, 1.30 MB

english, 2007

31

Platelet Collagen Receptors and Coagulation. A Characteristic Platelet Response as Possible Target for Antithrombotic Treatment

Johan W.M. Heemskerk, Marijke J.E. Kuijpers, Imke C.A. Munnix, Pia R.M. Siljander

Journal:

Trends in Cardiovascular Medicine

Year:

2005

Language:

english

File:

PDF, 1.68 MB

english, 2005

32

Hemostatic and Signaling Functions of Transfused Platelets

Sandra Cauwenberghs, Elisabeth van Pampus, Joyce Curvers, Jan-Willem N. Akkerman, Johan W.M. Heemskerk

Journal:

Transfusion Medicine Reviews

Year:

2007

Language:

english

File:

PDF, 442 KB

english, 2007

33

Correction of Coagulation in Dilutional Coagulopathy: Use of Kinetic and Capacitive Coagulation Assays to Improve Hemostasis

Saskia E.M. Schols, Johan W.M. Heemskerk, Elisabeth C.M. van Pampus

Journal:

Transfusion Medicine Reviews

Year:

2010

Language:

english

File:

PDF, 286 KB

english, 2010

34

Integrin &alpha;IIb&beta;3 and shear-dependent action of glycoprotein ib&alpha; stimulate platelet-dependent thrombin formation in stirred plasma

Jeffrey F.W. Keuren, Hans Ulrichts, Marion A.H. Feijge, Karly Hamulyak, Hans Deckmyn, Theo Lindhout, Johan W.M. Heemskerk

Journal:

Journal of Laboratory and Clinical Medicine

Year:

2003

Language:

english

File:

PDF, 147 KB

english, 2003

35

Glutathione oxidation in calcium- and p38 MAPK-dependent membrane blebbing of endothelial cells

Roosje M.A van Gorp, Sylvia Heeneman, Jos L.V Broers, Nancy M.H.J Bronnenberg, Maria C.E van Dam-Mieras, Johan W.M Heemskerk

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

2002

Language:

english

File:

PDF, 546 KB

english, 2002

36

Indirect regulation of Ca2+ entry by cAMP-dependent and cGMP-dependent protein kinases and phospholipase C in rat platelets

Johan W. M. HEEMSKERK, Marion A. H. FEIJGE, Stewart O. SAGE, Ulrich WALTER

Journal:

Year:

1994

Language:

english

File:

PDF, 927 KB

english, 1994

37

The Ca2+-Mobilizing Potency of α-Thrombin and Thrombin-Receptor-Activating Peptide on Human Platelets : Concentration and Time Effects of Thrombin-Induced Ca2+ Signaling

Johan W. M. Heemskerk, Marion A. H. Feijge, Lidewij Henneman, Jan Rosing, H. Coenraad Hemker

Journal:

Year:

1997

Language:

english

File:

PDF, 956 KB

english, 1997

38

Function of Glutathione Peroxidase in Endothelial Cell Vitality

Roosje M.A. van Gorp, Gerard Hornstra, Maria C.E. van Dam-Mieras, Johan W.M. Heemskerk

Journal:

Archives of Biochemistry and Biophysics

Year:

2000

Language:

english

File:

PDF, 112 KB

english, 2000

39

Membrane fluidity of non-activated and activated human blood platelets

Marion A.H. Feijge, Johan W.M. Heemskerk, Gerard Hornstra

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

1990

Language:

english

File:

PDF, 505 KB

english, 1990

40

Function of intracellular [Ca2+]i in exocytosis and transbilayer movement in human platelets surface-labeled with the fluorescent probe 1-(4-(trimethylammonio)phenyl)-6-phenyl-1,3,5-hexatriene

Johan W.M Heemskerk, Marion A.H Feijge, Harry A.M Andree, Stewart O Sage

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

1993

Language:

english

File:

PDF, 1023 KB

english, 1993

41

Turnover of galactolipids incorporated into chloroplast envelopes: An assay for galactolipid: Galactolipid galactosyltransferase

Johan W. Heemskerk, Gerard Bögemann, J.F.G.M. Wintermans

Journal:

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Year:

1983

Language:

english

File:

PDF, 980 KB

english, 1983

42

Spinach chloroplasts: localization of enzymes involved in galactolipid metabolism

Johan W.M. Heemskerk, Gerard Bögemann, J.F.G.M. Wintermans

Journal:

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Year:

1985

Language:

english

File:

PDF, 1.27 MB

english, 1985

43

Localization of galactolipid: galactolipid galactosyltransferase and acyltransferase in outer envelope membrane of spinach chloroplasts

Johan W.M. Heemskerk, Jef F.G.M. Wintermans, Jacques Joyard, Maryse A. Block, Albert-Jean Dorne, Roland Douce

Journal:

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Year:

1986

Language:

english

File:

PDF, 902 KB

english, 1986

44

Characterization of galactosyltransferases in spinach chloroplast envelopes

Johan W.M. Heemskerk, Frans H.H. Jacobs, Martin A.M. Scheijen, Johannes P.F.G. Helsper, Jef F.G.M. Wintermans

Journal:

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Year:

1987

Language:

english

File:

PDF, 1.57 MB

english, 1987

45

UDPgalactose-independent synthesis of monogalactosyldiacylglycerol. An enzymatic activity of the spinach chloroplast envelope

Johan W.M. Heemskerk, Frans H.H. Jacobs, Jef F.G.M. Wintermans

Journal:

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Year:

1988

Language:

english

File:

PDF, 997 KB

english, 1988

46

Influence of dietary fatty acids on membrane fluidity and activation of rat platelets

Johan W.M. Heemskerk, Marion A.H. Feijge, Rob Kalafusz, Gerard Hornstra

Journal:

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Year:

1989

Language:

english

File:

PDF, 1.42 MB

english, 1989

47

Effects of dietary fatty acids on signal transduction and membrane cholesterol content in rat platelets

Johan W.M. Heemskerk, Marion A.H. Feijge, Marianne A.G. Simonis, Gerard Hornstra

Journal:

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Year:

1995

Language:

english

File:

PDF, 1.05 MB

english, 1995

48

Rat platelets are deficient in internal Ca2+ release and require influx of extracellular Ca2+ for activation

Johan W.M. Heemskerk, Marion A.H. Feijge, Ellen Rietman, Gerard Hornstra

Journal:

Year:

1991

Language:

english

File:

PDF, 354 KB

english, 1991

49

Thromboxane receptor stimulation inhibits adenylate cyclase and reduces cyclic AMP-mediated inhibition of ADP-evoked responses in fura-2-loaded human platelets

Stewart O. Sage, Johan W.M. Heemskerk

Journal:

Year:

1992

Language:

english

File:

PDF, 434 KB

english, 1992

50

Shedding of procoagulant microparticles from unstimulated platelets by integrin-mediated destabilization of actin cytoskeleton

Sandra Cauwenberghs, Marion A.H. Feijge, Alan G.S. Harper, Stewart O. Sage, Joyce Curvers, Johan W.M. Heemskerk

Journal:

Year:

2006

Language:

english

File:

PDF, 270 KB

english, 2006